Alchemist’s disease is now the “sixth leading cause of death in the United States” (Alchemist’s Association) due to TTS progressive symptoms that gradually worsen over a span of four to twenty years. Yet Alchemies is not only a “disease Of Old age. ” (Alchemist’s Association) It is said that about five percent of people with this disease have younger-set Alchemist’s occurring in someone in their go’s or go’s. With the factor of age being removed, are there any medical risk factors that are known for the onset of this horrific disease?
A study with the researchers at the Mayo Clinic found that a combination of tests and factors has led to a “reliable prediction algorithm for the development of a mild cognitive impairment. (Miller) A mild cognitive impairment, also known as an MIMIC, is known as an intermediate stage between the expected downfall of cognitive process due to normal aging and the tragic declination of dementia. The study says that “a sizable fraction of MIMIC patients progress to the dementia of Alchemist’s Disease. (Miller) The publishers of the National Institute of Aging, the NINA, also believe that “people seem to be symptom-free, but toxic changes are taking place in the brain. ” (NINA) Other factors could include health conditions and family’s history of dementia. At a molecular level, the 23 pairs of chromosomes that humans possess eave over 30,000 genes biologically coded within them. Some chromosomes are now known for carrying a risk for Alchemist’s. One large risk for this disease correlates with a region on the 19th chromosome.
Nature. Com released an article saying that there are three variants of this chromosome: 2, 3, and 4. The POPE protein, the 4 variant of chromosome 19, does not have a clearly expressed function in the brain but is known to “raise a person’s risk of developing the disease fourfold…. With two copies, the risk increases twelve-fold. ” (Spinney) However, even if the person carries this mutation, it goes not mean that the person will develop the disease. Three other mutations of genes makes these carriers at risk for Alchemist’s.
The first is the Myeloid precursor protein (APP). This gene mutation was discovered in 1987, being the first found to inherit the carrier with a form of Alchemist’s. The second gene risk potentially carrying gene mutations is Prehensile-l (AS-I), known as the “most common cause of early-onset Alchemist’s. ” (Alchemist’s Association) Presenting-2 (AS-2), founded in 1 993, was the third gene carrying mutations that can also cause early-onset of Alchemist’s. Alchemist’s “irreversible” and “progressive” (NINA) properties cause different stages of this dementia to occur.
The first stage is known as the Mild Alchemist’s disease or early-stage. The symptoms start as simple cognitive malfunctions. Problems begin to occur with remembering names, forgetting things just read, misplacing valuable items, and “coming up with the right word or name. ” (Alchemist’s Association) In this early stage, a person is able to function independently such as working, driving, and partaking in social activities. Friends and family are said to begin to notice these difficulties and a errors may feel as if they are having “memory lapses. (Alchemist’s Association) To be sure that these symptoms truly are Alchemist’s at work, a doctor must perform a detailed medical examination to detect cognitive complications caused by this disease. The next stage of Alchemies s is known as Moderate Alchemist’s, also known as the middle-stage. The middle-stage is typically known to be the longest of the three stages. During this stage, an individual demands a greater level of care than they previously required. A person in this stage is known for having “greater difficulty performing tasks… But they may still remember significant details about their life. (Alchemist’s Association) Damage of the brain’s net cells is clear due to challenges performing monotonous tasks and expressing thoughts. Other noticeable symptoms include mental withdrawal, changes in sleep patterns, increases in wandering, personality changes, and confusion on time of day or where they are. The inevitable final stage of the disease is Severe Alchemist’s, known as the late-stage. In this stage, individuals begin to lose their ability to respond to the environment around them, convey a conversation, and eventually fail to control their movement.
They are able to speak some words and phrases, but expressing pain and Other feelings becomes extremely difficult. People in this stage also need full-time assistance, experience loss of physical ability like walking, sitting, and swallowing and fail to recall recent experiences. The worse side-effect to this stage is vulnerability to severe infections, such as pneumonia. Unfortunately, there is no cure for Alchemies at this present time. Though, there are several medications that are approved by the FDA to help treat symptoms of Alchemist’s.
These drugs include “O’Donnell (Aricept@), Representative (Exelon@), and Galantine (Razadyne@) are used to treat mild o moderate Alchemist’s (O’Donnell can be used for severe Alchemist’s as well). Meantime (Namenda@) is used to treat moderate to severe Alchemist’s. ” (NINA) These drugs help maintain skills such as thinking and memory but do not change the underlying downhill path of this disease. Fortunately, there are ongoing trials that could potentially lead to a cure down the road.
Right now, there is an investigation about the drug pigmentation and how it could possibly delay the onset for individuals considered by the algorithm for high-risk discussed above. “Evidence from animal and small-scale human studies suggest that pigmentation may prevent r reverse Alchemist’s-related pathology and symptoms… By stimulating mitochondria to divide. ” (Spinney) Even though a cure is not in the near future, this research has made it easier for doctors to identify Alchemist’s at early stages in order to implicate medication to help individuals deal with this disease’s symptoms.
Now understanding how Alchemies can be caused and its symptoms, many ask if they have any influence of this disease. Many experts believe that though there are many inevitable factors, there are a few risks that can eliminate. Some experts believe that there is a strong link teen risk of Alchemies s and serious head injury, especially when the trauma occurs repetitively or occurs in loss of consciousness. One can protect themselves from this by wearing helmets in sports, wearing seat belts when in a car, and making home a “fall-proof” place.
Another possible risk is a connection of the heart and head. Emerging evidence is beginning to link the brain’s health to one’s hearts health. The brain is “nourished by one of your body’s richest networks of blood vessels… Brain cells use at least 20 percent of the food and oxygen your blood carries. ” (Alchemies Association) Developing vascular dementia, another name for Alchemist’s, appears to increase when there is damaged heart or blood vessels from conditions such as high blood pressure, diabetes, heart disease, stroke, and high cholesterol.
Donated brain tissue has provided confirmation for this connection suggesting that “plaques and tangles are more likely to cause Alchemist’s symptoms if strokes or damage to the brain’s blood vessels are also present. ” (Alchemist’s Association) Alchemist’s is not what normal aging should be. It infects the minds of these individuals and steals their brains of communication, emotion, and function. But with the help of medication and research, there is hope that one day scientists will be able to alter the development of this disease and improve the life of people with Alchemist’s.
